top of page

Independent Publications

Coming Soon

Mentored Publications

Mechanism of Action of KL-50, a Novel Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. 

Huseman, E. D.; Lo, A.; Fedorova, O.; Elia, J. L.; Gueble, S. E.; Lin, K.; Sundaram, R. K.; Burgenske, D. M.; Oh, J.; Liu, J.; Menges, F. S.; Rees, M. G.; Ronan, M. M.; Roth, J. A.; Batista, V. S.; Crawford, J. M.; Sarkaria, J. N.; Pyle, A. M.; Bindra, R. S.*; Herzon, S. B. Chemrxiv. Cambridge: Cambridge Open Engage; 2023. DOI: 10.26434/chemrxiv-2023-zwj94

Mechanism-based Design of Agents that Selectively Target Drug-Resistant Glioma

Lin, K.; Gueble, S. E.; Sundaram, R. K.; Huseman, E. D.; Bindra, R. S.*; Herzon, S. B.*

Science 2022, 377, 502–511. DOI: 10.1126/science.abn7570

Synthesis and Cytotoxic Evaluation of Arimetamycin A and Its Daunorubicin and Doxorubicin Hybrids

Huseman, E. D.; Byl, J. W.; Chapp, S. M.; Schley, N. D.; Osheroff, N.; Townsend, S. D.*

ACS Cent. Sci. 2021, 7, 1327–1337. DOI: 10.1021/acscentsci.1c00040

De novo Synthesis of an L-Lemonose Thioglycoside Donor from D-Threonine

Huseman, E. D.; Townsend, S. D.* Tetrahedron Lett. 2021, 73, 153097.

DOI: 10.1016/j.tetlet.2021.153097

Luteolin Decreases EGFR-Mediated Cell Proliferation and Induces Apoptosis in Glioblastoma Cell Lines. 

Anson, D. M.; Wilcox, R. M.; Huseman, E. D.; Stump, T. A.; Paris, R. L.; Darkwah, B. O.; Lin, S.; Adegoke, A. O.; Gryka, R. J.; Jean-Louis, D. S.; Amos, S.*

Basic. Clin. Pharmacol. Toxicol. 2018, 123, 678–686. DOI: 10.1111/bcpt.13077

The DARK Side of Total Synthesis: Strategies and Tactics in Psychoactive Drug Production

Chambers, S. A.; DeSousa, J. M.; Huseman, E. D.; Townsend, S. D.*

ACS Chem. Neurosci. 2018, 9, 2307–2330. DOI: 10.1021/acschemneuro.7b00528

The Antiproliferative and Apoptotic Effects of Apigenin on Glioblastoma Cells

Stump, T. A.; Santee, B. N.; Williams, L. P.; Kunze, R. A.; Heinze, C. E.; Huseman, E. D.; Gryka, R. J.; Simpson, D. S.; Amos, S.* J. Pharm. Pharmacol. 2017, 69, 907–916. DOI: 10.1111/jphp.12718

Synthesis and Characterization of a Series of Chiral Alkoxymethyl Morpholine Analogs as Dopamine Receptor 4 (D4R) Antagonists

Witt, J.; McCollum, A. L.; Hurtado, M. A.; Huseman, E. D.; Jeffries, D. E.; Temple, K. J. Plumley, H. C.; Blobaum, A. L.; Lindsley, C. W.; Hopkins, C. R.*

Bioorg. Med. Chem. Lett. 2016, 26, 2481–2488. DOI: 10.1016/j.bmcl.2016.03.102

bottom of page